

Development of scleral contact lens correction: from the Renaissance era to modern lens designs
https://doi.org/10.33791/2222-4408-2025-1-54-63
Abstract
Scleral contact lenses are considered one of the most effective methods of optical correction for induced ametropia, particularly in cases of irregular corneal surface. Advancements in scleral lens materials and design have significantly expanded the indications for their fitting. However, ophthalmologists have insufficient awareness of this correction method and its potential in the optical rehabilitation of patients. Objective: to review and summarize the literature on the historical milestones in the development of scleral contact lenses and their application in modern ophthalmic practice. Methods. A literature analysis was conducted using the eLibrary and PubMed databases, covering publications from the last 30 years. Over 200 relevant articles were reviewed, of which 50 were included in this study. Results. This review outlines the history of scleral lens development, detailing key stages in their evolution. The characteristics of modern scleral lenses, including the materials used and the equipment for their fabrication, are described. The indications and contraindications for scleral lens fitting are also discussed. Conclusion. Scleral lenses are now widely available and are custom-manufactured based on individual patient parameters using highly gas-permeable materials. Their use enables optimal visual outcomes even in challenging clinical cases where other correction methods prove ineffective.
About the Authors
A. V. MyagkovRussian Federation
Alexander V. Myagkov, Dr. Sci. (Med.), Professor, Director of the National Myopia Institute; Professor at the Department of Ophthalmology, Krasnov Research Institute of Eye Diseases
7, Deguninskaya Str., Moscow, 127486
11 a, b, Rossolimo Str., Moscow, 119021
V. V. Averich
Russian Federation
Veronika V. Averich, Cand. Sci. (Med.), Researcher at the Department of Ocular Media Pathology, Krasnov Research Institute of Eye Diseases; Senior Researcher at the Department of Contact Lens Vision Correction, National Myopia Institute
7, Deguninskaya Str., Moscow, 127486
11 a, b, Rossolimo Str., Moscow, 119021
References
1. Phillips AJ, Speedwell L. Contact lenses. Elsevier Health Sciences, 2018. 672 p.
2. Barnett M, Johns LK. Contemporary scleral lenses: theory and application (Vol. 4). Bentham Science Publishers, 2017. 510 p.
3. Myagkov AV. Guidelines for medical optics. Part 2. Contact vision correction. Moscow: April, 2018. 321 р. (In Russ.)
4. Kivaev AA, Shapiro EI. Contact correction of vision: A textbook for interns, residents, students of the system of additional medical education. Moscow: LDM service, 2000. 224 p. (In Russ.)
5. Mandell RB. Contact lens practice: Hard and Flexible Lenses. Thomas Publisher, 1974. 819 p.
6. Ţălu Ş, Ţălu M, Giovanzana S, Shah RD. A brief history of contact lenses. Human and Veterinary Medicine. 2011;3(1):33–37.
7. Phani K, Gaurav K. Contact lens materials and modalities. Tr Ophtha Open Acc J. 2018;1(1)1–5. doi: 10.32474/TOOAJ.2018.01.000106
8. Conway MJ. Modern trends in contact lens materials development. The EYE GLAZ. 2019;3:40–45. (In Russ.) doi: 10.33791/2222-4408-2019-3-40-45
9. DeNaeyer GW. Profilometry. Using сorneo-scleral topography for scleral lens fitting. The EYE GLAZ. 2019;4:19–22. (In Russ.) doi: 10.33791/2222-4408-2019-4-19-22
10. Eddleston M. Optimum Infinite is a new era of oxygen permeability material for contact lenses. The EYE GLAZ. 2020;1:44– 46. (In Russ.) doi: 10.33791/2222-4408-2020-1-44-46
11. Yadykin AA, Listratov SV. Contact lens manufacturing technology. The EYE GLAZ. 2022;24(2):55–59. (In Russ.) doi: 10.33791/2222-4408-2022-2-55-59
12. Michaud L, Lipson M, Kramer E, Walker M. The official guide to scleral lens terminology. Cont Lens Anterior Eye. 2020 Dec;43(6):529–534. doi: 10.1016/j.clae.2019.09.006
13. Listratov SV, Bakalova NA, Averich VV. OKVision® SMARTFITTM scleral contact lens manufacturing technology. The EYE GLAZ. 2021;23(2):47–52 (In Russ.). doi: 10.33791/2222- 4408-2021-2-47-52
14. Kreps EO, Pesudovs K, Claerhout I, Koppen C. Mini-scleral lenses improve vision-related quality of life in keratoconus. Cornea. 2021 Jul 1;40(7):859–864. doi: 10.1097/ICO.0000000000002518. PMID: 32947413 15. Lim L, Lim EWL. Current perspectives in the management of keratoconus with contact lenses. Eye (Lond). 2020 Dec;34(12):2175–2196. doi: 10.1038/s41433-020-1065-z
15. Barnett M, Courey C, Fadel D, et al. CLEAR – Scleral lenses. Cont Lens Anterior Eye. 2021 Apr;44(2):270–288. doi: 10.1016/j.clae.2021.02.001
16. Barnett M, Mannis MJ. Contact lenses in the management of keratoconus. Cornea. 2011 Dec;30(12):1510–1516. doi: 10.1097/ICO.0b013e318211401f
17. Maharana PK, Dubey A, Jhanji V, et al. Management of advanced corneal ectasias. Br J Ophthalmol. 2016 Jan;100(1):34– 40. doi: 10.1136/bjophthalmol-2015-307059
18. Rathi VM, Mandathara PS, Taneja M, et al. Scleral lens for keratoconus: technology update. Clin Ophthalmol. 2015 Oct 28;9:2013–2018. doi: 10.2147/OPTH.S52483
19. Asena L, Altınörs DD. Clinical outcomes of scleral Misa lenses for visual rehabilitation in patients with pellucid marginal degeneration. Cont Lens Anterior Eye. 2016 Dec;39(6):420–424. doi: 10.1016/j.clae.2016.06.010
20. DeLoss KS, Fatteh NH, Hood CT. Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) scleral device compared to keratoplasty for the treatment of corneal ectasia. Am J Ophthalmol. 2014 Nov;158(5):974–982. doi: 10.1016/j.ajo.2014.07.016
21. Koppen C, Kreps EO, Anthonissen L, et al. Scleral lenses reduce the need for corneal transplants in severe keratoconus. Am J Ophthalmol. 2018 Jan;185:43–47. doi: 10.1016/j.ajo.2017.10.022
22. Chu HS, Wang IJ, Tseng GA, et al. Mini-scleral lenses for correction of refractive errors after radial keratotomy. Eye Contact Lens. 2018 Nov;44 Suppl 2:S164–S168. doi: 10.1097/ ICL.0000000000000437. PMID: 29023313
23. Parminder A, Jacobs DS. Advances in scleral lenses for refractive surgery complications. Curr Opin Ophthalmol. 2015 Jul;26(4):243–248. doi: 10.1097/ICU.0000000000000173
24. Barnett M, Lien V, Li JY, et al. Use of scleral lenses and miniscleral lenses after penetrating keratoplasty. Eye Contact Lens. 2016 May;42(3):185–189. doi: 10.1097/ICL.0000000000000163
25. Rocha GA, Miziara PO, Castro AC, Rocha AA. Visual rehabilitation using mini-scleral contact lenses after penetrating keratoplasty. Arq Bras Oftalmol. 2017 Jan-Feb;80(1):17–20. doi: 10.5935/0004-2749.20170006
26. Montalt JC, Porcar E, España-Gregori E, Peris-Martínez C. Visual quality with corneo-scleral contact lenses after intracorneal ring segment (ICRS) implantation for keratoconus management. Cont Lens Anterior Eye. 2019 Feb;42(1):111–116. doi: 10.1016/j.clae.2018.07.006
27. Romero-Jiménez M, Flores-Rodríguez P. Utility of a semi-scleral contact lens design in the management of the irregular cornea. Cont Lens Anterior Eye. 2013 Jun;36(3):146–150. doi: 10.1016/j.clae.2012.12.006
28. Fadel D, Kramer E. Potential contraindications to scleral lens wear. Cont Lens Anterior Eye. 2019 Feb;42(1):92–103. doi: 10.1016/j.clae.2018.10.024
29. Nau CB, Harthan J, Shorter E, et al. Demographic characteristics and prescribing patterns of scleral lens fitters: The SCOPE study. Eye Contact Lens. 2018 Sep;44 Suppl 1:S265–S272. doi: 10.1097/ICL.0000000000000399 31. Romero-Rangel T, Stavrou P, Cotter J, et al. Gas-permeable scleral contact lens therapy in ocular surface disease. Am J Ophthalmol. 2000 Jul;130(1):25–32. doi: 10.1016/s0002-9394(00)00378-0
30. Sharma N, Sah R, Priyadarshini K, Titiyal JS. Contact lenses for the treatment of ocular surface diseases. Indian J Ophthalmol. 2023 Apr;71(4):1135–1141. doi: 10.4103/IJO.IJO_17_23
31. Yuksel E, Bilgihan K, Novruzlu Ş, et al. The management of refractory dry eye with semi-scleral contact lens. Eye Contact Lens. 2018 May;44(3):e10–e12. doi: 10.1097/ ICL.0000000000000267
32. La Porta Weber S, Becco de Souza R, Gomes JÁP, Hofling-Lima AL. The use of the esclera scleral contact lens in the treatment of moderate to severe dry eye disease. Am J Ophthalmol. 2016 Mar;163:167–173.e1. doi: 10.1016/j.ajo.2015.11.034
33. Bavinger JC, DeLoss K, Mian SI. Scleral lens use in dry eye syndrome. Curr Opin Ophthalmol. 2015 Jul;26(4):319–324. doi: 10.1097/ICU.0000000000000171
34. Nunziata S, Petrini D, Dell’Anno S, et al. Customized scleral lenses: An alternative tool for severe dry eye disease – a case series. J Clin Med. 2024 Jul 4;13(13):3935. doi: 10.3390/jcm13133935
35. Fedotova K, Grabovetsky VR, Novikov SA, Ezugbaya M. Miniscleral lenses in the treatment of patients with dry eye syndrome (first own experience). Ophthalmology Reports. 2019;12(1):5–12. (In Russ.) doi: 10.17816/OV201915-12
36. Papakostas TD, Le HG, Chodosh J, Jacobs DS. Prosthetic replacement of the ocular surface ecosystem as treatment for ocular surface disease in patients with a history of Stevens-Johnson syndrome/toxic epidermal necrolysis. Ophthalmology. 2015 Feb;122(2):248–253. doi: 10.1016/j. ophtha.2014.08.015
37. Grey F, Carley F, Biswas S, Tromans C. Scleral contact lens management of bilateral exposure and neurotrophic keratopathy. Cont Lens Anterior Eye. 2012 Dec;35(6):288–291. doi: 10.1016/j.clae.2012.07.009
38. Margolis R, Thakrar V, Perez VL. Role of rigid gas-permeable scleral contact lenses in the management of advanced atopic keratoconjunctivitis. Cornea. 2007 Oct;26(9):1032–1034. doi: 10.1097/ICO.0b013e3181245172.
39. Alipour F, Kheirkhah A, Jabarvand Behrouz M. Use of mini scleral contact lenses in moderate to severe dry eye. Cont Lens Anterior Eye. 2012 Dec;35(6):272–276. doi: 10.1016/j. clae.2012.07.006
40. Nguyen MTB, Thakrar V, Chan CC. EyePrintPRO therapeutic scleral contact lens: indications and outcomes. Can J Ophthalmol. 2018 Feb;53(1):66–70. doi: 10.1016/j.jcjo.2017.07.026
41. Lim P, Ridges R, Jacobs DS, Rosenthal P. Treatment of persistent corneal epithelial defect with overnight wear of a prosthetic device for the ocular surface. Am J Ophthalmol. 2013 Dec;156(6):1095–1101. doi: 10.1016/j.ajo.2013.06.006
42. Rosenthal P, Cotter JM, Baum J. Treatment of persistent corneal epithelial defect with extended wear of a fluid-ventilated gas-permeable scleral contact lens. Am J Ophthalmol. 2000 Jul;130(1):33–41. doi: 10.1016/s0002-9394(00)00379-2
43. Vilares Morgado R, Moura R, Moreira R, et al. New promising therapeutic approach for refractory corneal epithelial defects. Cureus. 2023 May 22;15(5):e39324. doi: 10.7759/cureus.39324
44. Özbek Z, Kefeli I. Scleral contact lens to preserve a corneal graft in chronic lagophthalmos. Turk J Ophthalmol. 2024 Apr 19;54(2):103–107. doi: 10.4274/tjo.galenos.2024.68253.
45. Shah-Desai SD, Aslam SA, Pullum K, et al. Scleral contact lens usage in patients with complex blepharoptosis. Ophthalmic Plast Reconstr Surg. 2011 Mar-Apr;27(2):95–98. doi: 10.1097/IOP.0b013e3181d07408
46. Chaudhary S, Kate A, Basu S, Shanbhag SS. Impact of symblepharon management with ocular surface reconstruction on scleral lens fitting in eyes with chronic cicatrizing conjunctivitis and keratopathy. Cornea. 2024 Aug 1;43(8):975– 981. doi: 10.1097/ICO.0000000000003437
47. Severinsky B, Lenhart P. Scleral contact lenses in the pediatric population-Indications and outcomes. Cont Lens Anterior Eye. 2022 Jun;45(3):101452. doi: 10.1016/j.clae.2021.101452
48. Mortensen ZQ, Simmons BA, Shriver EM, et al. Scleral contact lens as initial management in a neonate with a large upper eyelid coloboma. Ophthalmic Plast Reconstr Surg. 2022 Jan-Feb 01;38(1):e10–e13. doi: 10.1097/IOP.0000000000002057
Review
For citations:
Myagkov A.V., Averich V.V. Development of scleral contact lens correction: from the Renaissance era to modern lens designs. The EYE GLAZ. 2025;27(1):54-63. (In Russ.) https://doi.org/10.33791/2222-4408-2025-1-54-63