Changes in the anatomical and functional parameters of the eye when using glasses with Stellest™ lenses in children with progressive myopia

Relevance. Myopia is one of the most common refractive pathologies in the world. By 2050, according to WHO 2015, more than half of the world’s population will suffer from myopia, which will lead to the risk of developing pathologies associated with the progression of myopia, such as glaucoma, macular degeneration and retinal detachment. The use of various modern methods to control myopia can slow down the progression of myopia, which potentially reduces the risks of complications. Objective: to evaluate changes in the anatomical and functional parameters of the eye (clinical refraction, axial length, accommodation functions) in children with progressive myopia corrected with glasses with Stellest lenses in different age groups. Materials and methods. The study was conducted on the basis of the Eye Microsurgery Clinic of the Stavrapol State Medical University. Glasses with Stellest lenses were assigned to 80 children aged 8 to 16 years. The average age of the children was 11 ± 0.12 years. The children were divided into three age groups: 1st – primary school; 2nd -middle school; Group 3 – senior school. After the examination, the children were selected glasses with Stellest lenses. The average period of wearing glasses with Stellest lenses was 12 months. Clinical refraction, axial length and accommodation functions were evaluated during the observation. Results. The change in refraction depended on the age of the child. The greatest increase in refraction by 0.40 ± 0.02 D was observed in the younger age group, and the smallest (0.27 ± 0.02 D) in children of secondary school age. In the group of children of senior school age, the increase in refraction was +0.32 ± 0.03 D. The axial length of the eye in children of the primary school group after 12 months of wearing glasses with Stellest lenses signifi cantly increased by an average of 0.28 ± 0.03 mm. This axial growth of the eye correlates with an increase in myopic refraction in the same group of children. In the group of children of senior school age, the growth of PZO was 0.1 ± 0.04 mm. There was an increase in the accommodation reserve, the positive relative accommodation and the relative accommodation in all groups. Conclusions. The study showed that wearing glasses with Stellest lenses helps to reduce the rate of progression of myopia and increase the accommodative functions of the eye, which improves the adaptive capabilities and performance of the visual analyzer in all age groups of schoolchildren

1. Volkova L.P. Modern organization of children’s vision protection. Prevention of myopia as a disease of regulation. Russian Pediatric Ophthalmology. 2020;1:5–13. (In Russ.) https://doi.org/10.25276/2307-6658-2020-1-5-13

2. Hodun N. Integration of physical, mental, social and spiritual components in the implementation of a healthy lifestyle of modern high schoolchildren. Science and Society. 2022;2(2):147–153. (In Russ.) https://doi.org/10.31470/2786-6327/2022/2/147-153

3. Naidoo K.S., Fricke T.R., Frick K.D. et al. Potential lost productivity resulting from the global burden of myopia: systematic review, meta-analysis, and modeling. Ophthalmology. 2019;126:338–346. https://doi.org/10.1016/j.ophtha.2018.10.029

4. Medina A. The progression of corrected myopia. Graefes Arch Clin Exp Ophthalmol. 2015;253(8):1273–1277. https://doi.org/10.1007/s00417-015-2991-5

5. Mikhailova L.A., Katargina L.A. Resources of the pediatric ophthalmological service and the effectiveness of their use. Russian Pediatric Ophthalmology. 2021;16(4):47–54. (In Russ.) https://doi.org/10.17816/rpoj84931

6. Smith E.L., Hung L.F. The role of optical defocus in regulating refractive development in infant monkeys. Vision Res. 1999;39(8):1415–1435. https://doi.org/10.1016/S0042-6989(98)00229-6

7. Accommodation: A Guide for Doctors. L.A. Katargina, ed. Moscow; 2012. (In Russ.)

8. Rudnicka A.R., Kapetanakis V.V., Wathern A.K. et al. Global variations and time trends in the prevalence of childhood myopia, a systematic review and quantitative metaanalysis: implications for aetiology and early prevention. Br J Ophthalmol. 2016;100(7):882–890. https://doi.org/10.1136/bjophthalmol-2015-307724

9. COMET Group. Myopia stabilization and associated factors among participants in the Correction of Myopia Evaluation Trial (COMET). Invest Oph Vis Sci. 54(13):7871–7984. https:// doi.org/10.1167/iovs.13-12403

10. Naidoo K.S., Fricke T.R., Frick K.D. et al. Potential lost productivity resulting from the global burden of myopia: sysmytematic review, meta-analysis, and modeling. Ophthalmology. 2019;126(3):338–346. https://doi.org/10.1016/j.ophtha.2018.10.029

11. Wildsoet C.F., Chia A., Cho P. et al. IMI – Interventions Myopia Institute: interventions for controlling myopia onset and progression report. Invest Ophthalmol Vis Sci. 2019;60(3):106– 131. https://doi.org/10.1167/iovs.18-25958

12. Morgan I.G., French A.N., Ashby R.S. et al. The epidemics of myopia: Aetiology and prevention. Prog Retin Eye Res. 2018;62:134–149. https://doi.org/10.1016/j.preteyeres.2017.09.004

13. Wu L.J., You Q.S., Duan J.L. et al. Prevalence and associated factors of myopia in highschool students in Beijing. PLoS One. 2015;10(3):1–12. htts://doi.org/10.1371/journal. pone.0120764

14. Fricke T.R., Jong M., Naidoo K.S. Global prevalence of visual impairment associated with myopic macular degeneration and temporal trends from 2000 through 2050: systematic review, meta-analysis and modelling. Br J Ophthalmol. 2018;102(7):855–862. https://doi.org/10.1136/bjophthalmol-2017-311266

15. Li S.Y., Li S.M., Zhou Y.H. et al. Effect of undercorrection on myopia progression in 12-year-old children. Graefes Arch Clin Exp Ophthalmol. 253(8):1363–1368. https://doi.org/10.1111/opo.12305

16. Vasudevan B., Esposito C., Peterson C. et al. Under-correction of human myopia – is it myopigenic?: a retrospective analysis of clinical refraction data. J Optom. 2014;7(3):147–152. https://doi.org/10.1016/j.optom.2013.12.007

17. Wong Y.-L., Sabanayagam C., Ding Y. et al. Prevalence, risk factors, and impact of myopic macular degeneration on visual impairment and functioning among adults in Singapore. Invest Ophthalmol Vis Sci. 2018;59:460313. https://doi.org/10.1167/iovs.1824032

18. Lam C.S.Y., Tang W.C., Tse D.Y.-Y. et al. Defocus incorporated multiple segments (DIMS) spectacle lenses slow myopia progression: a 2-year randomised clinical trial. Br J Ophthalmol. 2020;104(3):363–368. https://doi.org/10.1136/bjophthalmol-2018-313739

19. Tarutta E.P., Tarasova N.A., Arutyunyan S.G., Maksimova M.V. Comparative analysis of the magnitude of the distance and lens-induced objective accommodative response in patients with different refraction. Bulletin of Ophthalmology. 2017;133(4):37–41. (In Russ.) https://doi.org/10.17116/oftalma2017133437-41

20. Wallman J., Gottlieb M.D., Rajaram V. et al. Local retinal regions control local eye growth and myopia. Science. 1987;237(4810):73–77. https://doi.org/10.1126/science.3603011

21. Bao J., Yang A., Huang Y. et al. One-year myopia control effi cacy of spectacle lenses with aspherical lenslets. Br J Ophthalmol. 2022;106(8):1171–1176. https://doi.org/10.1136/bjophthalmol-2020-318367

22. Proskurina O.P., Markova E.Y., Brzheskij V.V. et al. The prevalence of myopia in schoolchildren in some regions of Russia. Ophthalmology in Russia. 2018;15(3):348–353. (In Russ.) https://doi.org/10.18008/1816-5095-2018-3-348-353

23. Markova E.Y., Pron’ko N.A., Aminulla L.V. et al. To the question of school myopia. Оphthalmology. 2018;15(1):87–91. https://doi.org/10.18008/1816-5095-2018-1-87-91

24. Wildsoet C.F., Chia A., Cho P. et al. Imi – interventions for controlling myopia onset and progression report. Invest Ophthalmol Vis Sci. 2019;60:106–131. https://doi.org/10.1167/iovs.18-25958

25. Myagkov A.V., Myagkov D.A. Optical methods for the management of progressive myopia. The EYE GLAZ. 2023;25(2):151–162. (In Russ.) https://doi.org/10.33791/2222-4408-2023-2-151-162

26. Chamberlain P., Peixoto-de-Matos S.C., Logan N.S. et al. A 3-year randomized clinical trial of MiSight lenses for my opia control. Optom Vis Sci. 2019;96:556–567. https://doi.org/10.1097/OPX.0000000000001410

27. Benavente-Perez A., Nour A., Troilo D. Short interruptions of imposed hyperopic defocus earlier in treatment are more effective at preventing myopia development. Sci Rep. 2019;9(1):11459. https://doi.org/10.1038/s41598-019-480093

28. Chamberlain P., Peixoto-de-Matos S.C., Logan N.S. et al. A 3-year randomized clinical trial of MiSight lenses for myopia control. Optom Vis Sci. 2019;96:556–567. https://doi.org/10.1097/OPX.0000000000001410

29. Novolodsky A.I., Pecheneva A.V., Ozornina Ya.V. Changes in the axial length of the eye and refraction in children with progressive myopia while wearing defocused contact lenses. The EYE GLAZ. 2022;24(2):17–24. (In Russ.) https://doi.org/10.33791/2222-4408-2022-2-17-24

30. Huang Y., Li X., Wu J. et al. Effect of spectacle lenses with aspherical lenslets on choroidal thickness in myopic children: a 2-year randomised clinical trial. Br J Ophthalmol. 2022;0:1– 6. http://dx.doi.org/10.1136/bjo-2022-321815

31. Qin Z., Peng T., Zhang Z. et al. Myopia progression and stabilization in school-aged children with single-vision lenses. Acta Ophthalmol. 2022;100(4):e950–e956. https://doi.org/10.1111/aos.15038

32. Li S.M., Wei S., Atchison D.A. et al. Annual incidences and progressions of myopia and high myopia in Chinese schoolchildren based on a 5-year cohort study. Invest Ophthalmol Vis Sci. 2022;63(1):8. https://doi.org/10.1167/iovs.63.1.8

33. Li X., Huang Y., Yin Z. et al. Myopia control effi cacy of spectacle lenses with aspherical lenslets: results of a 3-year follow-up study. American Journal of Ophthalmology. 2023;253:160–168. https://doi.org/10.1016/j.ajo.2023.03.03

34. Gao Y., Lim, E.W., Drobe B. Impact of myopia control spectacle lenses with highly aspherical lenslets on peripheral visual acuity and central visual acuity with peripheral gaze. Ophthalmic Physiol Opt. 2023;43:566–571. https://doi.org/10.1111/opo.13127

35. Khvatova N.V., Slishalova N.N. Available methods of the examination of the eye accommodation in the ophthalmological outpatient department (materials from the Conference on Accomodation, Yaroslavl, 2019). The EYE GLAZ. 2019;21(2(126)):59–68. (In Russ.) https://doi.org/10.33791/2222-4408-2019-2-59-68

36. Avetisov S.E., Myagkov A.V., Egorova A.V. et al. Results of a two-year clinical study of myopia control with bifocal defocus- inducing soft contact lenses. Bulletin of Ophthalmology. 2021;137(3):5–12. (In Russ.) https://doi.org/10.17116/oftalma20211370315

37. Bao J., Huang Y., Li X. et al. Spectacle lenses with aspherical lenslets for myopia control vs single-vision spectacle lenses: a randomized clinical trial. JAMA Ophthalmol. 2022;140(5):472– 478. https://doi.org/10.1001/jamaophthalmol.2022.0401

38. Proskurina O.V., Tarasova N.A., Markosyan G.A. et al. Adaptation and quality of vision in glasses with lenses for the control of Stellest myopia with built-in high-spherical microlenses. Russian Pediatric Ophthalmology. 2022;17(2):5–12. (In Russ.) https://doi.org/10.17816/rpoj97296

39. Myagkov A.V., Poskrebysheva Zh.N., Zhabina O.A., Myagkov D.A. Epidemiology of myopia in children of the Russian Federation and analysis of its control methods. The EYE GLAZ. 2021;23(2):7–18. (In Russ.) https://doi.org/10.33791/2222440820212718