Terminology in orthokeratology: conceptual systematization, semantics, and practical application
https://doi.org/10.33791/2222-4408-2026-2-141-148
Abstract
Background. Orthokeratology is one of the most rapidly developing approaches to refractive error correction and myopia control worldwide. Different terminological traditions have emerged, often varying considerably between national ophthalmological schools. As orthokeratology continues to develop, this terminological heterogeneity has become a significant issue. It complicates the comparison of research findings, the conduct of meta-analyses, and the translation of evidence into routine clinical practice. Purpose: To systematize the terminology used in orthokeratology, clarify semantic differences between Russian-language and international concepts, identify controversial definitions, and propose recommendations for the appropriate use of terms in clinical practice and scientific communication. Materials and methods. A targeted search of PubMed/MEDLINE and eLIBRARY.RU was conducted for publications from 1962 to 2025 using the following search terms: orthokeratology, ortho-k, corneal reshaping, reverse geometry, myopia control, ортокератология, and ОК-терапия. The analysis included consensus documents, including BCLA CLEAR Orthokeratology 2021 and the IMI Clinical Management Guidelines 2019, randomized clinical trials, systematic reviews, Russian clinical guidelines, and regulatory documents. Thirty-four peer-reviewed sources that met the inclusion criteria were selected. Results. At least six English-language terms or near-synonyms for the core concept were identified: orthokeratology, ortho-k, corneal refractive therapy, vision shaping treatment, accelerated orthokeratology, and overnight vision correction. Four Russian-language equivalents were also identified: ортокератология, ОК-терапия, ночные линзы and корнеорефракционная терапия. The term orthokeratologist was found to be absent from professional standards in the United States, the European Union, and the Russian Federation and should therefore be regarded as professional jargon used to refer to ophthalmologists and optometrists who practice orthokeratology. The terms open design and closed design were not found in English-language consensus sources. Instead, lens designs are classified by geometric configuration, such as toric or spherical design, and by manufacturing approach, such as stock or custom-designed lenses. Several concepts were found to be insufficiently structured from a semantic standpoint, including the Jessen factor, compression factor, and myopia control efficacy. Conclusion. Standardization of orthokeratology terminology is necessary for the accurate interpretation of clinical studies, transparent communication with patients, and appropriate delineation of professional competencies. In the Russian Federation, the term ophthalmologist specializing in orthokeratology is recommended for use in official documents instead of orthokeratologist. The terms open design and closed design should be replaced with descriptive characteristics of lens design.
Keywords
About the Authors
A. V. MyagkovRussian Federation
Alexander V. Myagkov, Dr. Sci. (Med.), Professor, Director; Professor, Department of Ophthalmology
7 Deguninskaya St., Moscow, 127486; 11 A, B Rossolimo St., Moscow, 119021
S. G. Khomiakov
Russian Federation
Sergei G. Khomiakov, Dr. Sci. (Med.), Professor, Department of Ophthalmology
7 Deguninskaya St., Moscow, 127486
References
1. Vincent SJ, Cho P, Chan KY, et al. BCLA CLEAR – Orthokeratology. Cont Lens Anterior Eye. 2021;44(2):240–269. doi:10.1016/j.clae.2021.02.010
2. Swarbrick HA. Orthokeratology review and update. Clin Exp Optom. 2006;89(3):124–143. doi:10.1111/j.1444-0938.2006.00055.x
3. Gifford KL, Richdale K, Kang P, et al. IMI – Clinical Management Guidelines Report. Invest Ophthalmol Vis Sci. 2019;60(3):M184–M203. doi:10.1167/iovs.18-25977
4. Lipson MJ, Huang X, Lim R. Current perspectives on myopia control with orthokeratology. Prog Retin Eye Res. 2023; 94:101125. doi:10.1016/j.preteyeres.2022.101125
5. Bullimore MA, Richdale K, Sinnott LT, et al. The risk of microbial keratitis with overnight corneal reshaping lenses. Optom Vis Sci. 2013;90(9):937–944. doi:10.1097/OPX.0b013e31829cfe02
6. Nichols JJ, Marsich MM, Nguyen M, et al. Overnight orthokeratology. Optom Vis Sci. 2000;77(5):252–259. doi:10.1097/00006324-200005000-00012
7. Mountford J. An analysis of the changes in corneal shape and refractive error induced by accelerated orthokeratology. Int Contact Lens Clin. 1997;24(4):128–144. doi:10.1016/S0892-8967(97)00055-2
8. Sun Y, Xu F, Zhang T, et al. Orthokeratology to control myopia progression: A meta-analysis. PLoS One. 2015;10(4):e0124535. doi:10.1371/journal.pone.0124535
9. Chen R, Liu X, Gao W, et al. Orthokeratology for myopia control: a three-year longitudinal analysis of axial length shortening and age-stratified efficacy. Eye Vis (Lond). 2025;12(1):27. doi:10.1186/s40662-025-00345-8
10. Cho P, Cheung SW. Retardation of myopia in orthokeratology (ROMIO) study: A 2-year randomized clinical trial. Invest Ophthalmol Vis Sci. 2012;53(11):7077–7085. doi:10.1167/iovs.12-10565
11. Hiraoka T, Kakita T, Okamoto F, et al. Long-term effect of overnight orthokeratology on axial elongation in childhood myopia: A 5-year follow-up study. Invest Ophthalmol Vis Sci. 2012;53(7):3913–3919. doi:10.1167/iovs.11-8453
12. Marcotte-Collard R, Simard P, Michaud L. Analysis of two orthokeratology lens designs and comparison of their optical effects on the cornea. Eye Contact Lens. 2018;44(5):322–329. doi:10.1097/ICL.0000000000000382
13. Alharbi A, Swarbrick HA. The effects of overnight orthokeratology lens wear on corneal thickness. Invest Ophthalmol Vis Sci. 2003;44(6):2518–2523. doi:10.1167/iovs.02-1005
14. Chen J, Xie H, Zhu X, et al. Clinical safety and efficacy of orthokeratology contact lenses with different treatment zone designs. J Ophthalmol. 2025;2025:8897165. doi:10.1155/2025/8897165
15. Chen Z, Xue F, Zhou J, et al. Prediction of orthokeratology lens decentration with corneal elevation. Optom Vis Sci. 2017;94(9):903–907. doi:10.1097/OPX.0000000000001107
16. Zhou Y, Wang C, Chen Y. The efficacy of orthokeratology lenses with smaller back optic zone: A meta-analysis. Ophthalmic Physiol Opt. 2024;44(6):1254–1262. doi:10.1111/opo.13259
17. Lu W, Jiang T, Song Z, et al. Comparison of two main orthokeratology lens designs in controlling myopia progression. Front Med (Lausanne). 2022;9:798314. doi:10.3389/fmed.2022.798314
18. Koo S, Kim H, Lee S, et al. Development of a machine-learning-based tool for determining optimal orthokeratology lens parameters. Transl Vis Sci Technol. 2024;13(1):13. doi:10.1167/tvst.13.1.13
19. Wu LY, Wang YM, Xu XL, et al. Investigation of the relationship between contact lens design parameters and refractive power change through parametric mathematical modeling. Heliyon. 2022;8(11):e11698. doi:10.1016/j.heliyon.2022.e11698
20. Chen C, Cheung SW, Cho P. Myopia control using toric orthokeratology (TO-SEE study). Invest Ophthalmol Vis Sci. 2013;54(10):6510–6517. doi:10.1167/iovs.13-12373
21. López-López M, García-Montero M, Ruiz-Pomeda A, et al. Long-term efficacy and safety of orthokeratology with toric lens designs in moderate to high corneal astigmatism. Eye Contact Lens. 2024;50(1):14–18. doi:10.1097/ICL.0000000000000942
22. Chen J, Huang W, Zhu R, et al. Infl uence of overnight orthokeratology lens treatment zone decentration on myopia progression. J Ophthalmol. 2019;2019:2596953. doi:10.1155/2019/2596953
23. VanderVeen DK, Kraker RT, Pineles SL, et al. Use of orthokeratology for the prevention of myopic progression in children: A report by the American Academy of Ophthalmology. Ophthalmology. 2019;126(4):623–636. doi:10.1016/j.ophtha.2018.11.026
24. Charm J, Cho P. High myopia-partial reduction ortho-k: A 2-year randomized study. Optom Vis Sci. 2013;90(6):530– 539. doi:10.1097/OPX.0b013e318294c3cb
25. Wan K, Lau JK, Cheung SW, Cho P. Orthokeratology with increased compression factor (OKIC): Study design and preliminary results. BMJ Open Ophthalmol. 2020;5(1):e000345. doi:10.1136/bmjophth-2019-000345
26. González-Méijome JM, Villa-Collar C, Queirós A, et al. Pilot study on the infl uence of corneal biomechanical properties over the short term in response to corneal refractive therapy for myopia. Cornea. 2008;27(4):421–426. doi:10.1097/ICO.0b013e31816583c3
27. Lam AKC, Hon Y, Leung SYY, Shu-Ho L, Chong J, Lam DCC. Association between long-term orthokeratology responses and corneal biomechanics. Sci Rep. 2019;9(1):12566. doi:10.1038/s41598-019-49041-z
28. Kim J, Lim DH, Han SH, Chung TY. Predictive factors associated with axial length growth and myopia progression in orthokeratology. PLoS One. 2019;14(7):e0218140. doi:10.1371/journal.pone.0218140
29. Santodomingo-Rubido J, Cheung SW, Villa-Collar C. A new look at the myopia control efficacy of orthokeratology. Cont Lens Anterior Eye. 2024;47(5):102186. doi:10.1016/j.clae.2023.101186
30. Lin W, Li N, Lu K, Li Z, Zhuo X, Wei R. The relationship between baseline axial length and axial elongation in myopic children undergoing orthokeratology. Ophthalmic Physiol Opt. 2023;43(1):122-131. doi:10.1111/opo.13070
31. Vincent SJ, Tan Q, Ng ALK, et al. Higher-order aberrations and axial elongation in myopic children treated with orthokeratology. Cont Lens Anterior Eye. 2020;43(3):217–222. doi:10.1016/j.clae.2019.03.009
32. Lau JK, Vincent SJ, Collins MJ, Cheung SW, Cho P. Ocular higher-order aberrations and axial eye growth in young Hong Kong children. Sci Rep. 2018;8(1):6726. doi:10.1038/s41598-018-25279-3
33. Hui W, Huang J, Zhang S, et al. Application of orthokeratology on myopia control and its effect on ocular higher-order aberrations. Front Med (Lausanne). 2022;9:993223. doi:10.3389/fmed.2022.993223
34. Hiraoka T, Kakita T, Okamoto F, et al. Influence of ocular wavefront aberrations on axial length elongation in myopic children undergoing overnight orthokeratology. Sci Rep. 2020;10(1):6695. doi:10.1038/s41598-020-63560-4
Review
For citations:
Myagkov A.V., Khomiakov S.G. Terminology in orthokeratology: conceptual systematization, semantics, and practical application. The EYE GLAZ. 2026;28(2):141-148. (In Russ.) https://doi.org/10.33791/2222-4408-2026-2-141-148
JATS XML






















