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Association between the outcomes of ReLEx® SMILE and the degree of baseline myopia
https://doi.org/10.33791/2222-4408-2025-3-210-216
Abstract
Background. Myopia is the most common refractive disorder of the eye globally. One of the methods for surgical correction of myopia is ReLEx® SMILE (Small Incision Lenticule Extraction). The impact of baseline myopia severity on postoperative outcomes remains debated due to inconsistent literature findings. Purpose: To assess the association between the outcomes of ReLEx® SMILE and baseline myopia severity. Materials and methods. This prospective study included 78 patients (156 eyes) aged 18 to 35 years who underwent refractive correction using the ReLEx® SMILE procedure. Patients were stratified into three groups by myopia severity: Group I – low myopia (n = 31 eyes), Group II – moderate myopia (n = 87 eyes), Group III – high myopia (n = 38 eyes). The follow-up period was six months. Results. Uncorrected visual acuity (UCVA) of 0.9–1.0 was achieved in 100% (Group I), 93% (Group II), and 82% (Group III) of eyes, with statistically significant differences between the groups (p < 0.017). No statistically significant differences in the efficacy index were observed (p = 0.78): efficacy was 100% in Groups I and II, and 97.1% in Group III. The safety index was 100% in Groups I and III and 98% in Group II, with no statistically significant difference (p = 0.458). Refractive regression occurred in one case each in Groups I and III, while no cases of regression were observed in Group II. Conclusion. Refractive correction using the ReLEx® SMILE technique provides predictable and stable correction for all degrees of myopia and myopic astigmatism, with no significant differences in complication rates across severity groups.
About the Authors
A. S. Kozlova
Ural State Medical University;
Professorskaya Plus Eye Surgery Clinic
Russian Federation
Russian Federation
Alina S. Kozlova, Postgraduate student, Department of Ophthalmology, Ophthalmologist
3, Repina Str., Ekaterinburg, 620028
15, Vaynera Str., Ekaterinburg, 620014
S. A. Korotkikh
Ural State Medical University;
Professorskaya Plus Eye Surgery Clinic
Russian Federation
Russian Federation
Sergey A. Korotkikh, Dr. Sci. (Med), Professor and Head, Department of Ophthalmology, Ophthalmologist
3, Repina Str., Ekaterinburg, 620028
15, Vaynera Str., Ekaterinburg, 620014
S. Yu. Vasilieva
Ural State Medical University
Russian Federation
Russian Federation
Sofia Yu. Vasilieva, 6th-year medical student, Faculty of General Medicine
3, Repina Str., Ekaterinburg, 620028
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Review
For citations:
Kozlova A.S., Korotkikh S.A., Vasilieva S.Yu. Association between the outcomes of ReLEx® SMILE and the degree of baseline myopia. The EYE GLAZ. 2025;27(3):210-216. (In Russ.) https://doi.org/10.33791/2222-4408-2025-3-210-216
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