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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">glazmag</journal-id><journal-title-group><journal-title xml:lang="ru">The EYE ГЛАЗ</journal-title><trans-title-group xml:lang="en"><trans-title>The EYE GLAZ</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2222-4408</issn><issn pub-type="epub">2686-8083</issn><publisher><publisher-name>Академия медицинской оптики и оптометрии</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33791/2222-4408-2026-1-5-14</article-id><article-id custom-type="elpub" pub-id-type="custom">glazmag-774</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Разработка модели машинного обучения для прогноза прогрессирования миопии у детей, использующих очки с периферическим дефокусом</article-title><trans-title-group xml:lang="en"><trans-title>Development of a machine learning model for predicting myopia progression in children wearing peripheral defocus spectacle lenses</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-1139-0731</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шихалиева</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shikhalieva</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шихалиева Эльвира Абдулжалиловна, аспирант</p><p>127486, г. Москва, Бескудниковский б-р, д. 59а</p></bio><bio xml:lang="en"><p>Elvira A. Shikhalieva, Postgraduate Student</p><p>59a Beskudnikovsky Boulevard, Moscow, 127486</p></bio><email xlink:type="simple">mellifluous.el@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7387-7669</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Костенев</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kostenev</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Костенев Сергей Владимирович, доктор медицинских наук, старший научный сотрудник отдела лазерной рефракционной хирургии</p><p>127486, г. Москва, Бескудниковский б-р, д. 59а</p></bio><bio xml:lang="en"><p>Sergey V. Kostenev, Dr. Sci. (Med.), Senior Res earcher, Department of Laser Refractive Surgery</p><p>59a Beskudnikovsky Boulevard, Moscow, 127486</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6732-1226</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кечин</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kechin</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кечин Евгений Владимирович, кандидат медицинских наук, магистр прикладных математики и физики, начальник отдела реализации инновационных программ, трансфера и коммерциализации технологий; доцент кафедры общей врачебной практики и поликлинической терапии</p><p>127486, г. Москва, Бескудниковский б-р, д. 59а; 125993, г. Москва, ул. Баррикадная, д. 2/1, стр. 1</p></bio><bio xml:lang="en"><p>Evgeny V. Kechin, Cand. Sci. (Med.), MSc in Applied Mathematics and Physics, Head of the Department of Innovation Program Implementation, Technology Transfer and Commercialization; Associate Professor, Department of General Practice and Outpatient Therapy</p><p>59a Beskudnikovsky Boulevard, Moscow, 127486; 2/1 Barrikadnaya St., Bldg. 1, Moscow, 125993</p></bio><email xlink:type="simple">evgeny.kechin@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-4702-3983</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Муртазалиева</surname><given-names>П. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Murtazalieva</surname><given-names>P. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Муртазалиева Патимат Камалудиновна, врач-офтальмолог, ассистент кафедры глазных болезней</p><p>367023, Республика Дагестан, г. Махачкала, ул. М.М. Джамбулатова, д. 60а</p></bio><bio xml:lang="en"><p>Patimat K. Murtazalieva, Ophthalmologist, Assistant Professor, Department of Ophthalmology</p><p>60a Dzhambulatova St., Makhachkala, 367023, Republic of Dagestan</p></bio><email xlink:type="simple">patimur82@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НМИЦ «МНТК “Микрохирургия глаза” им. акад. С.Н. Федорова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S. Fyodorov Eye Microsurgery Federal State Institution</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>НМИЦ «МНТК “Микрохирургия глаза” им. акад. С.Н. Федорова»;  ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S. Fyodorov Eye Microsurgery Federal State Institution; Russian Medical Academy of Continuous Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Дагестанский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Dagestan State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>01</day><month>04</month><year>2026</year></pub-date><volume>28</volume><issue>1</issue><fpage>5</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Академия медицинской оптики и оптометрии, 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Академия медицинской оптики и оптометрии</copyright-holder><copyright-holder xml:lang="en">Академия медицинской оптики и оптометрии</copyright-holder><license xlink:href="https://www.theeyeglaz.com/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://www.theeyeglaz.com/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://www.theeyeglaz.com/jour/article/view/774">https://www.theeyeglaz.com/jour/article/view/774</self-uri><abstract><p>Актуальность. Близорукость является главной причиной снижения зрительных функций. В клинической практике используются различные методики лечения и профилактики прогрессирования данного заболевания. Особое внимание уделяется изучению возможностей применения искусственного интеллекта в прогнозировании и лечении миопии. Посредством машинного обучения разрабатываются новые и совершенствуются существующие модели, позволяющие прогнозировать результат лечения на основе исходных данных. Цель: разработать и протестировать модель машинного обучения для прогнозирования прогрессирования миопии у детей, использующих дизайн очковых линз с периферическим дефокусом, через 12 месяцев ношения. Материалы и методы. Сформирован набор данных о 48 глазах 48 пациентов, для которых был проведен подбор дизайна очковых линз с периферическим дефокусом. 8 моделей машинного обучения для бинарной классификации (XGBoost, Random Forest, Gradient Boosting, LightGBM, Extra Trees, Logistic Regression, Decision Tree, K-Nearest Neighbors) разрабатывались с использованием языка программирования Python 3 и библиотек scikit-learn, XGBoost, LightGBM. В качестве целевой переменной был прогноз результата применения перифокальных очков в виде бинарного признака: благоприятный исход (24 глаза) и неблагоприятный (24 глаза). Благоприятным исходом признавался результат более –1,00 дптр, который соответствовал значению годового градиента прогрессирования через 12 месяцев после оптической коррекции, а неблагоприятный – –1,00 дптр и менее (по математической логике). Для разработки и тестирования моделей машинного обучения общий набор данных был разделен на обучающую и тестовую выборку в соотношении 67:33. Оценка важности признаков моделей проводилась на основе метода значимости признаков (feature_importances). Результаты. Наилучшее качество по целевой метрике ROC AUC на тестовом наборе данных показала модель XGBoost (ROC AUC 0,906), точность (accuracy) прогнозирования исхода составила 0,875, чувствительность – 0,875, специфичность – 0,875. Наиболее важными признаками для прогноза стали следующие показатели: кератометрия слабого меридиана (Kmin до 0,382), сфероэквивалент (до 0,217), радиус кривизны (R до 0,184), переднезадняя ось (до 0,102), возраст пациента (0,064), кератометрия сильного меридиана (Kmax до 0,051). Заключение. Предложенная модель показала отличное качество по целевой метрике ROC AUC для прогнозирования результата применения дизайна очковых линз с периферическим дефокусом через 12 месяцев ношения у детей. Для практического использования данной модели разработан калькулятор.</p></abstract><trans-abstract xml:lang="en"><p>Background. Myopia remains one of the leading causes of visual impairment worldwide. A wide range of therapeutic and preventive strategies is currently applied in clinical practice to slow myopia progression. In recent years, increasing attention has been directed toward the use of artificial intelligence (AI) for predicting disease progression and treatment outcomes. Machine learning techniques enable the development of predictive models based on baseline clinical data, thereby improving individualized treatment planning. Purpose: To develop and validate a machine learning model for predicting myopia progression at the 12-month follow-up in children wearing peripheral defocus spectacle lenses. Materials and methods. A dataset comprising 48 eyes of 48 pediatric patients fitted with peripheral defocus spectacle lenses was analyzed. Binary classification models were developed using Python 3 and the scikit-learn, XGBoost, and LightGBM libraries. Eight machine learning algorithms were evaluated: XGBoost, Random Forest, Gradient Boosting, LightGBM, Extra Trees, Logistic Regression, Decision Tree, and K-Nearest Neighbors. The outcome variable was defined as a binary indicator of treatment effectiveness: favorable outcome (24 eyes) – annual myopia progression less than −1.00 diopters at 12 months; unfavorable outcome (24 eyes) – progression of −1.00 diopters or greater. The dataset was divided into training and test sets in a 67:33 ratio. Feature importance was assessed using built-in feature importance methods. Results. The highest predictive performance on the test dataset was demonstrated by the XGBoost model, with a ROC AUC of 0.906. The model achieved an accuracy of 0.875, sensitivity of 0.875, and specificity of 0.875. The most influential predictors of treatment outcome were: minimum keratometry (Kmin) at baseline (0.382), baseline spherical equivalent refraction (0.217), baseline corneal radius of curvature (0.184), baseline axial length (0.102), patient age (0.064), and maximum keratometry (Kmax) at baseline (0.051). Conclusion. The proposed machine learning model demonstrated excellent predictive performance for forecasting the outcome of peripheral defocus spectacle lens wear in children at the 12-month follow-up. A clinical decision-support calculator based on this model has been developed for practical application.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>машинное обучение</kwd><kwd>периферический дефокус</kwd><kwd>миопия</kwd><kwd>перифокальные очки</kwd><kwd>годовой градиент прогрессирования</kwd></kwd-group><kwd-group xml:lang="en"><kwd>machine learning</kwd><kwd>peripheral defocus</kwd><kwd>myopia</kwd><kwd>peripheral defocus spectacle lenses</kwd><kwd>annual myopia progression rate</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">авторы не получали финансирование при проведении исследования и написании статьи.</funding-statement><funding-statement xml:lang="en">The authors received no funding for the research or preparation of this article.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Fricke TR, Jong M, Naidoo KS, Sankaridurg P, Naduvilath TJ, Ho SM, Wong TY, Resnikoff S. 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