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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">glazmag</journal-id><journal-title-group><journal-title xml:lang="ru">The EYE ГЛАЗ</journal-title><trans-title-group xml:lang="en"><trans-title>The EYE GLAZ</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2222-4408</issn><issn pub-type="epub">2686-8083</issn><publisher><publisher-name>Академия медицинской оптики и оптометрии</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33791/2222-4408-2025-4-343-352</article-id><article-id custom-type="elpub" pub-id-type="custom">glazmag-728</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Коморбидность заболеваний глаз и пародонта (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Comorbidity of ocular and periodontal diseases: A literature review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1597-1876</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трухан</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Trukhan</surname><given-names>D. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трухан Дмитрий Иванович, доктор медицинских наук, доцент, профессор кафедры поликлинической терапии и внутренних болезней</p><p>644043, г. Омск, ул. Ленина, д. 12</p></bio><bio xml:lang="en"><p>Dmitry I. Trukhan, Dr. Sci. (Med.), Associate Professor, Professor of the Department of Outpatient Therapy and Internal Diseases</p><p>12 Lenina Str., Omsk, 644043</p></bio><email xlink:type="simple">dmitry_trukhan@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8190-4121</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедев</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedev</surname><given-names>O. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лебедев Олег Иванович, доктор медицинских наук, профессор, заведующий кафедрой офтальмологии</p><p>644043, г. Омск, ул. Ленина, д. 12</p></bio><bio xml:lang="en"><p>Oleg I. Lebedev, Dr. Sci. (Med.), Professor, Head of the Department of Ophthalmology</p><p>12 Lenina Str., Omsk, 644043</p></bio><email xlink:type="simple">leo.55@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сулимов</surname><given-names>А. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Sulimov</surname><given-names>A. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сулимов Анатолий Филиппович, доктор медицинских наук, профессор, заведующий кафедрой челюстно-лицевой хирургии</p><p>644043, г. Омск, ул. Ленина, д. 12</p></bio><bio xml:lang="en"><p>Anatoly F. Sulimov, Dr. Sci. (Med.), Professor, Head of the Department of Maxillofacial Surgery</p><p>12 Lenina Str., Omsk, 644043</p></bio><email xlink:type="simple">afsulimov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4721-6605</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трухан</surname><given-names>Л. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Trukhan</surname><given-names>L. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трухан Ларисcа Юрьевна, кандидат медицинских наук, врач-стоматолог кафедры челюстно-лицевой хирургии</p><p>644043, г. Омск, ул. Ленина, д. 12</p></bio><bio xml:lang="en"><p>Larissa Y. Trukhan, Cand. Sci. (Med.), Dentist, Department of Maxillofacial Surgery</p><p>12 Lenina Str., Omsk, 644043</p></bio><email xlink:type="simple">larissa_trukhan@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Омский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>14</day><month>12</month><year>2025</year></pub-date><volume>27</volume><issue>4</issue><fpage>343</fpage><lpage>352</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Академия медицинской оптики и оптометрии, 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Академия медицинской оптики и оптометрии</copyright-holder><copyright-holder xml:lang="en">Академия медицинской оптики и оптометрии</copyright-holder><license xlink:href="https://www.theeyeglaz.com/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://www.theeyeglaz.com/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://www.theeyeglaz.com/jour/article/view/728">https://www.theeyeglaz.com/jour/article/view/728</self-uri><abstract><p>Существенную часть офтальмологической патологии составляют проявления общих или системных заболеваний. Болезни пародонта относятся к числу наиболее распространенных заболеваний человека и первой причины потери зубов у взрослых. В начале XXI века сформировалась концепция «пародонтальной медицины», рассматривающая взаимосвязи патологии пародонта с системными заболеваниями организма. Несмотря на анатомическую близость глаз и полости рта, взаимосвязь между заболеваниями глаз и болезнями пародонта, возможные механизмы этой связи в отечественной литературе не рассматриваются. Цель представленного обзора – обобщение имеющихся данных о коморбидности глазных болезней и патологии пародонта. Мы провели поиск в информационных базах Pubmed и Scopus источников, опубликованных за период 01.01.2011 до 23.02.2025 г., в которых рассматривалась эта взаимосвязь. В итоговый обзор были включены 44 статьи. Результаты эпидемиологических и клинических исследований, рассмотренных в обзоре, позволяют предполагать наличие коморбидности между рядом глазных болезней (возрастная макулярная дегенерация, диабетическая ретинопатия, катаракта, глаукома, синдром сухого глаза, увеит) и патологией пародонта. К возможным механизмам этой связи относятся: гематогенная транслокация пародонтопатических микроорганизмов и медиаторов воспаления, взаимодействие по оси «рот – кишечник – глаз» и непрямое, опосредованное взаимодействие в рамках мультиморбидности по треугольникам «рот – кардиометаболическое заболевание – глаз» и «рот – иммуноопосредованное заболевание – глаз». Представленный обзор демонстрирует необходимость проведения дальнейших проспективных исследований для уточнения взаимосвязи между широко распространенными и серьезными заболеваниями глаз с патологией пародонта. Обзор подчеркивает важность междисциплинарных подходов в понимании системных последствий заболеваний пародонта и их потенциального влияния на здоровье глаз.</p></abstract><trans-abstract xml:lang="en"><p>A considerable proportion of ocular disorders represent manifestations of systemic diseases. Periodontal diseases rank among the most prevalent chronic conditions worldwide and are the leading cause of tooth loss in adults. In the early 21st century, the concept of periodontal medicine emerged, emphasizing the bidirectional relationship between periodontal pathology and systemic conditions. Despite the anatomical proximity of the eyes and the mouth, the association between ocular and periodontal diseases and the potential mechanisms underlying this link have received little attention in the Russian literature. This review summarizes current evidence on the comorbidity between ocular disorders and periodontal pathology. A systematic search of PubMed and Scopus databases identified publications from January 1, 2011, to February 23, 2025, examining this association. Forty-four studies met the inclusion criteria. Epidemiological and clinical data suggest comorbidity between several ocular diseases–age-related macular degeneration, diabetic retinopathy, cataract, glaucoma, dry eye disease, and uveitis–and periodontal pathology. Proposed mechanisms include hematogenous dissemination of periodontopathogenic microorganisms and inflammatory mediators, interactions along the oral–gut–eye axis, and indirect multimorbidity pathways, including oral–cardiometabolic–eye and oral–immune-mediated–eye links. The review highlights the need for further prospective studies to elucidate the association between prevalent and clinically significant ocular diseases and periodontal pathology. It underscores the importance of interdisciplinary approaches in understanding the systemic consequences of periodontal diseases and their potential impact on ocular health.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>возрастная макулярная дегенерация</kwd><kwd>катаракта</kwd><kwd>глаукома</kwd><kwd>синдром сухого глаза</kwd><kwd>диабетическая ретинопатия</kwd><kwd>пародонтит</kwd></kwd-group><kwd-group xml:lang="en"><kwd>age-related macular degeneration</kwd><kwd>cataract</kwd><kwd>glaucoma</kwd><kwd>dry eye disease</kwd><kwd>diabetic retinopathy</kwd><kwd>periodontitis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Balta MG, Papathanasiou E, Blix IJ, Van Dyke TE. Host Modulation and Treatment of Periodontal Disease. 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