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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">glazmag</journal-id><journal-title-group><journal-title xml:lang="ru">The EYE ГЛАЗ</journal-title><trans-title-group xml:lang="en"><trans-title>The EYE GLAZ</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2222-4408</issn><issn pub-type="epub">2686-8083</issn><publisher><publisher-name>Академия медицинской оптики и оптометрии</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33791/2222-4408-2021-2-33-39</article-id><article-id custom-type="elpub" pub-id-type="custom">glazmag-245</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Ранние критерии диагностики неврита зрительного нерва на фоне оптикомиелита Девика</article-title><trans-title-group xml:lang="en"><trans-title>Early Criteria for the Diagnosis of Optic Neuritis in the Setting of Davic’s Disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Камилов</surname><given-names>Х. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kamilov</surname><given-names>Kh. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Камилов Халиджан Мухаммаджанович, доктор медицинских наук, профессор, заведующий кафедрой офтальмологии</p><p>100007, Узбекистан, Ташкент, ул. Паркентская, 51</p></bio><bio xml:lang="en"><p>Kamilov Khalidjan Mukhammadjanovich, Dr. Sci. (Med.), Professor, Head of the Department of Ophthalmology</p><p>51, Parkent Str., Tаshkent, 100007, Uzbekistan</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Касимова</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kasimova</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Касимова Мунирахон Садикжановна, доктор медицинских наук, профессор кафедры офтальмологии</p><p>100007, Узбекистан, Ташкент, ул. Паркентская, 51</p></bio><bio xml:lang="en"><p>Kasimova Munirakhon Sadikjanovna, Dr. Sci. (Med.), Professor of the Department of Ophthalmology</p><p>51, Parkent Str., Tаshkent, 100007, Uzbekistan</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хамраева</surname><given-names>Г. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Khamraeva</surname><given-names>G. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хамраева Гавхар Хусановна, кандидат медицинских наук, ассистент кафедры офтальмологии</p><p>100007, Узбекистан, Ташкент, ул. Паркентская, 51</p></bio><bio xml:lang="en"><p>Khamraeva Gavkhar Khusanovna, Cand. Sci. (Med.), Assistant of the Department of Ophthalmology</p><p>51, Parkent Str., Tаshkent, 100007, Uzbekistan</p></bio><email xlink:type="simple">gavhar08021982@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ташкентский институт усовершенствования врачей</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Tаshkent Institute of Postgrаduаte Medicаl Educаtion</institution><country>Uzbekistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>26</day><month>06</month><year>2021</year></pub-date><volume>23</volume><issue>2</issue><fpage>33</fpage><lpage>39</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Академия медицинской оптики и оптометрии, 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Академия медицинской оптики и оптометрии</copyright-holder><copyright-holder xml:lang="en">Академия медицинской оптики и оптометрии</copyright-holder><license xlink:href="https://www.theeyeglaz.com/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://www.theeyeglaz.com/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://www.theeyeglaz.com/jour/article/view/245">https://www.theeyeglaz.com/jour/article/view/245</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Неврит зрительного нерва (НЗН) более чем в половине случаев является первым симптомом оптикомиелита Девика (ОМ). Дифференциальная диагностика неврита зрительного нерва в клинической практике врача-офтальмолога затруднена, что связано с однотипностью клинической картины воспалительного и демиелинизирующего неврита зрительного нерва на ранних стадиях заболевания. Подход к ведению этих больных различен и требует точной дифференцировки уже на начальных этапах развития.</p><p>Цель исследования – определение ранних объективных критериев диагностики состояния зрительного анализатора при неврите зрительного нерва вследствие оптикомиелита Девика.</p><p>Материал и методы исследования. Под нашим наблюдением находился 31 больной (51 глаз), контрольную группу составили 12 (24 глаза) здоровых лиц. Методами исследования служили стандартные офтальмологические и специальные методы – оптическая когерентная томография, зрительные вызванные потенциалы, магнитно-резонансная томография головного и спинного мозга.</p></sec><sec><title>Результаты</title><p>Результаты. При оптическом неврите на фоне оптикомиелита с помощью оптической когерентной томографии выявлены меньшие размеры площади диска зрительного нерва и нейроретинального пояска, снижение макулярного объема и толщины макулы. Также отмечено снижение объема комплекса ганглиозных клеток сетчатки и внутреннего плексиформного слоя</p></sec><sec><title>Выводы</title><p>Выводы. На начальных стадиях оптикомиелита необходимо своевременное проведение оптической когерентной томографии сетчатки, исследование зрительных вызванных потенциалов, а также магнитно-резонансной томографии головного и спинного мозга. Назначение соответствующего лечения на ранней стадии заболевания позволяет снизить скорость аксональной дегенерации и развития атрофии диска зрительного нерва.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Optic neuritis is the first symptom of Davic’s disease in more than half of cases. Differential diagnosis of optic neuritis in the clinical practice is complicated due to the uniformity of the clinical pattern of inflammatory and demyelinating optic neuritis in the early stages of the disease. The approach to the management of patients with Davic’s disease is varied and requires a precise differentiation at the initial stages of its development.</p></sec><sec><title>Purpose</title><p>Purpose. To determine early objective criteria for diagnosing the optic neuritis in the setting of Davic’s disease.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. We observed 31 patients (51 eyes), while the control group consisted of 12 healthy individuals (12 eyes). Research methods were both standard ophthalmic and specialized – optical coherence tomography, visual evoked potential test, magnetic resonance imaging of the brain and spinal cord.</p></sec><sec><title>Results</title><p>Results. In patients with optic neuritis in the setting of Davic’s disease, optical coherence tomography revealed a smaller area of the optic nerve disc and neuroretinal belt as well as a decrease in macular volume and macular thickness. A reduction of the retinal ganglion cell complex and the inner plexiform layer was also revealed.</p></sec><sec><title>Conclusion</title><p>Conclusion. At the initial stages of Davic’s disease, it is necessary to conduct optical coherence tomography of the retina, perform visual evoked potential test as well as magnetic resonance imaging of the brain and spinal cord. Appropriate treatment at an early stage of the disease can reduce the rates of axonal degeneration and optic disc atrophy development.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>неврит зрительного нерва</kwd><kwd>оптикомиелит Девика</kwd><kwd>оптическая когерентная томография сетчатки</kwd><kwd>зрительные вызванные потенциалы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>optic neuritis</kwd><kwd>Davic’s disease</kwd><kwd>optical coherence tomography of the retina</kwd><kwd>visual evoked potentials</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Камилов Х.М., Касимова М.С., Хамраева Г.Х. Морфофункциональные методы оценки динамики неврита зрительного нерва. Национальный журнал глаукома. Россия. 2017,16:37–42.</mixed-citation><mixed-citation xml:lang="en">Kamilov Kh.M., Kasimova M.S., Khamraeva G.Kh. 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